Challenges and Opportunities for Primary Cancer Prevention – Self-paced module – IARC-ESMO Cancer Prevention Learning and Capacity-Building Initiative

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Date of the recording: 16 November 2021

Webinar organized with the support of and in collaboration with the European Society for Medical Oncology (ESMO).

INTRODUCTION BY

Dr Béatrice Lauby-Secretan

Deputy Head, Evidence Synthesis and Classification Branch

International Agency for Research on Cancer, Lyon, France

About Dr Béatrice Lauby-Secretan

SPEAKERS

CANCER MODIFIABLE RISK FACTORS: OPPORTUNITIES AND CHALLENGES FOR CANCER PREVENTION

Professor David Hunter

Richard Doll Professor of Epidemiology and Medicine and Director of the Translational Epidemiology Unit

University of Oxford, Oxford, United Kingdom

The World Health Organization estimates that 30–50% of all cancer cases are preventable. There is strong scientific evidence about the role of a number of modifiable risk factors and protective factors in the incidence of and mortality from some of the most common cancer types around the world, such as lung cancer, colorectal cancer, breast cancer, and cervical cancer. What is the current status of that evidence, and how far have we progressed?

Short biography: Professor David Hunter

David Hunter is the Richard Doll Professor of Epidemiology and Medicine and Director of the Translational Epidemiology Unit at the Nuffield Department of Population Health, University of Oxford, United Kingdom. He founded the Program in Genetic Epidemiology and Statistical Genetics at Harvard University and was co-chair of the steering committee of the Breast and Prostate Cancer Cohort Consortium at the United States National Cancer Institute (NCI). He was co-director of the NCI Cancer Genetic Susceptibility Markers project, focused on genome-wide association studies, and was Dean for Academic Affairs and Acting Dean at the Harvard T.H. Chan School of Public Health. He is the Chief Science Adviser to Our Future Health, a major new national initiative in the United Kingdom that aims to return genomic information to consenting participants.

CANCER PREVENTION PERSPECTIVES BEYOND REDUCED CARCINOGEN EXPOSURE

Professor Bernard W. Stewart

Professor | Co-Editor of the 2020 World Cancer Report

University of New South Wales, Sydney, Australia

Decreased risk of lung cancer after smoking cessation epitomizes primary cancer prevention. Comparable responses to alcohol consumption, exposure to ultraviolet radiation, and human papillomavirus (HPV) infection remain crucial. Reduced cancer incidence may also be targeted for risk factors not involving recognized carcinogens. More broadly, health impacts due to inequalities offer the prospect of reducing a spectrum of diseases. However, even the immediate goal of avoiding exposure to carcinogens may fail because of beliefs and expectations.

Short biography: Professor Bernard W. Stewart

Professor Bernard W. Stewart is appointed to the Faculty of Medicine and Health, University of New South Wales, Sydney (Australia). His research interests involve all aspects of cancer prevention. With a PhD from the University of London, he is professionally qualified as a chemist and a lawyer. For IARC he has contributed to the Monographs programme variously across 100 volumes and has co-edited World Cancer Report as published from 2003 to 2020, Professor Stewart was awarded an Order of Australia honour for his services to medicine in the field of environmental carcinogenesis.

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Resource Content

Dr Béatrice Lauby-Secretan (3 min.)

Professor David Hunter (18 min.)

Professor Bernard W. Stewart (22 min.)

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