MANUAL: IARC Atlas – Using HPV tests for cervical cancer screening and managing HPV-positive women – a practical online guide

For health workers, nurses, midwives and physicians

By Joshi S, Basu P, Lucas E

2023

This practical guide covers the natural history of cervical cancer, the principles of HPV testing and different HPV tests for screening, steps for the collection of specimens for HPV testing, interpretation of the test results, and management of screen-positive women, including women living with HIV. It is based on the latest World Health Organization (WHO) guidelines on screening and management of screen-positive women:

• WHO guideline for screening and treatment of cervical pre-cancer lesions for cervical cancer prevention, second edition
• WHO guideline for screening and treatment of cervical pre-cancer lesions for cervical cancer prevention, second edition: use of mRNA tests for human papillomavirus (HPV)